Autism Treatment – Neurological Inflammation

Inflammation is known to be a big problem in chronic illness. Inflammation is always a problem in degenerative conditions we see in our country like diabetes, heart disease, arthritis, autoimmune disorders, and cancer, and it is even more problematic when the inflammation is chronic. We also see a problem with inflammation in Autism, especially neurological inflammation. There are several markers that can indicate inflammation that may be impacting these kids neurologically, tumor necrosis factor and interferon gamma are two.

Many children with Autism can have an issue with digestive inflammation and particularly, inflammatory bowel disease. But any type of inflammation whether it is in the gut, the blood stream, whether it is from a virus or a vaccine reaction or food sensitivities, it can negatively impact the brain. Inflammation in the brain can affect kids both globally and locally too, and can be particularly impactful on the temporal lobes. The temporal lobes are found on the side of the head and the left side is where some of the language areas are. When you have inflammation in those areas, blood flow can be decreased which hampers the ability for the blood to deliver oxygen. You can see that can be very problematic.

But the good news is there are many remedies that have been implemented that can have a positive change on neurological inflammation. Actos is a medication that have been used on individuals with Autism with fairly good success to help reduce neurological inflammation. Actos was originally a medication to control blood sugar for diabetics and then it was discovered that it could positively impact the way the cells in the body produce inflammation. Spironolactone is another medication to aid in controlling inflammation, also used at first to treat other conditions. It can be used to treat hirsutism which is an overproduction of testosterone in women and can regulate potassium and sodium which is useful in edema or swelling, especially of the lower extremities. Hyperbaric oxygen therapy is also an effective treatment for inflammation in Autism and it helps in two different ways. It increases blood flow and thereby oxygenation to the brain but the pressure of the chamber also seems to be helpful in treating inflammation as well. Turmeric is a very interesting herbal remedy for inflammation. It is an Indian spice with the active ingredient called curcumin. It is showing good results in children with Autism for both gut and neurological inflammation. As you do more research you will certainly hear more about inflammation, not only as a big problem in chronic illness today but also in the Autism community. But, as discussed in this article, there are remedies that can help.

Digital Medicine Platform for Treatment of Cognitive Disorder

Akili, a pioneer in therapeutic prescription digital medicine has closed successfully it’s $55 million financing Series C trial of medicine. This funding follows a successful trial, including study, developing and testing a novel digital medicine named AKL- T01. This flagship product of Akili aimed to treat a type of cognitive disorder- attention deficit/hyperactivity disorder (ADHD). Once approved and launched commercially, it would be the first digital and standalone therapeutic medicine for ADHD. Company’s other product in the pipeline and research, AKL-T02 will treat autism spectral disorder (ASD) or what simply known as autism.

Autism refers to another type of cognitive disorder, particularly in children, making them difficult to interact socially. The repetitive behavior and underdeveloped speech and verbal communication render them vulnerable in society. The reason behind autism could be genetic as well as environmental influence.

The above news has brought in a new ray of hope for an autism patient where there is no specific traditional medicine is available for its cure. This new development has the potential for treating this disorder, probably with more efficiency.

This funding will also help to advance products in the pipeline for treating multi sclerosis (MS) and depression. After approval by the U.S. Food and Drug Administration (FDA), it will be launched commercially for the patients. According to Akili AKL-T01 would be a standalone treatment for ADHD.

The company’s founder and CEO Eddie Martucci is quite happy with the response of investors and welcomed the financing. He said this financing indicates faith of people in his company’s potential in digital medicines and growth. According to him, the company will continue to grow and supply novel solutions in the redefined healthcare sector.

Akini Interactive is a company who believes in transforming healthcare through its digital therapeutics medicine solving Neuro-cognitive disorders. It believes in targeting specific cognitive area or nerve which has been suppressed by the dysfunction. The treatment includes, interestingly, not any pill, but customized action video games for patients to play.

Video games are designed by neuroscientists and entertainer engineered with algorithms to treat a cognitive disorder like depression. According to the company, highly-interactive and highly engaging games provide a therapeutic experience to patients which actually benefit them. Through high-end therapeutics interactive video games, the specific regions of the brain could become functional which has been suppressed by the disorder, improving the condition of the patient. There would second by second tracking of patient’s cognitive response and data available for any improvement in the patient’s condition.

AKL- T01 if approved by the FDA and then it would certainly indicate towards the acceptance of new healthcare solutions for patients. It has the capability to transform the whole healthcare process and system in coming years. This funding will boost the confidence of other investors, which are planning to invest or come together for such digital medicine research and development in the future and those patients who are searching for new areas to treat disorders like autism could be more than happy to read such positive news.